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BPC-157 Research Profile

Research Use

BPC-157 (Body Protection Compound 157) is a 15-amino acid synthetic peptide derived from human gastric juice protein sequences. It is widely investigated in tissue regeneration, tendon repair, and gut mucosal healing paradigms.

BPC-157 Quick Technical Specifications

Category
Healing & Tissue Repair
Elimination Half-Life
4 hours (short plasma half-life; tissue binding prolonged)
Storage Protocol
Refrigerated (2°C-8°C)
Status
Research Use
OE
Written by OnePeptideShip Editorial Team
Reviewed by Dr. Aris Thorne, MD, Board Certified Endocrinology Advisor
Updated September 2026

Mechanism of Action & Biochemical Context

BPC-157 (Body Protection Compound 157) is a 15-amino acid synthetic peptide derived from human gastric juice protein sequences. It is widely investigated in tissue regeneration, tendon repair, and gut mucosal healing paradigms.

Storage, Reconstitution & Stability Guidelines

Prior to reconstitution, lyophilized BPC-157 powder should be stored away from light between 2°C and 8°C for short-term access, or -20°C for long-term preservation. Once reconstituted with Bacteriostatic Water (0.9% benzyl alcohol preservative), maintain strict refrigeration between 2°C and 8°C. Do not freeze liquid solution.

Cited Scientific References

  1. Sikiric P, et al. Stable gastric pentadecapeptide BPC 157 in tissue healing. Curr Pharm Des. 2018.
  2. Seiwerth S, et al. BPC 157 and blood vessels. Curr Pharm Des. 2014.
  3. Chang CH, et al. The promoting effect of BPC-157 on tendon healing involves tendon outgrowth. J Appl Physiol. 2011.

Calculate BPC-157 Syringe Units

Input your vial mg and BAC water mL to calculate exact U-100 draw units.

Open BPC-157 Calculator →

Frequently Asked Questions

Adding 2mL of Bacteriostatic Water is the standard for a 5mg vial. This creates a concentration of 2,500mcg/mL, making a 250mcg dose equal exactly 10 units on a U-100 syringe - clean, easy math. Some researchers prefer 1mL of water for a denser 5mg/mL concentration, but this requires drawing only 5 units per dose, which is a very small and harder-to-measure volume.

It depends entirely on how much water you added. Using the standard 2mL in a 5mg vial (2,500mcg/mL): 250mcg = 10 units. Using 1mL of water (5,000mcg/mL): 250mcg = 5 units. Always use the calculator above and enter your actual water volume to get the correct unit draw.

Yes, absolutely. This combination is widely known as the "Wolverine Stack" and is one of the most common research protocols. The two peptides work on completely different biological pathways (BPC-157 on VEGF/angiogenesis, TB-500 on actin regulation) and do not react negatively in the syringe. Draw BPC-157 first, then pull TB-500 into the same syringe. Calculate each peptide's units independently.

When stored correctly in the refrigerator at 2 - 8°C with Bacteriostatic Water (which contains bacteriostatic benzyl alcohol), reconstituted BPC-157 remains potent for approximately 28 to 30 days. Do not freeze reconstituted peptide, as this can damage the molecular structure. Lyophilized (dry, unmixed) vials can be stored in the freezer for 1-2 years.

Both are valid, and the choice depends on the research goal. Subcutaneous (SubQ) injection into the abdominal fat is preferred for systemic healing (e.g., gut repair, whole-body anti-inflammation). Intramuscular (IM) injection near the injury site (e.g., into the calf for an Achilles tendon injury) is favored by some researchers for localized, targeted tissue repair.

BPC-157 Acetate is the standard injectable salt form. BPC-157 Arginate is a more stable salt specifically engineered to survive stomach acid, making it effective when administered orally (swallowed as a capsule or dissolved in water) for gastrointestinal conditions like leaky gut, Crohn's disease, or IBS. If you are injecting, Acetate is perfectly appropriate.

Most research protocols run 4 to 6 weeks of daily dosing (usually twice daily at 250mcg per injection), followed by a 2 to 4-week washout period. For acute injuries, some researchers use shorter, high-intensity cycles of 2 weeks at higher doses (500mcg twice daily), then taper. For chronic gut conditions, longer cycles of 8-12 weeks are sometimes explored.