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MK-677 Research Profile

Research Use

MK-677 (Ibutamoren) is an orally active, non-peptide selective agonist of the ghrelin receptor. It continuously stimulates profound, long-lasting increases in endogenous GH and IGF-1 levels.

MK-677 Quick Technical Specifications

Category
GH Secretagogues
Elimination Half-Life
approx. 2 to 6 hours
Storage Protocol
Refrigerated (2°C-8°C)
Status
Research Use
OE
Written by OnePeptideShip Editorial Team
Reviewed by Dr. Aris Thorne, MD, Board Certified Endocrinology Advisor
Updated September 2026

Mechanism of Action & Biochemical Context

MK-677 (Ibutamoren) is an orally active, non-peptide selective agonist of the ghrelin receptor. It continuously stimulates profound, long-lasting increases in endogenous GH and IGF-1 levels.

Storage, Reconstitution & Stability Guidelines

Prior to reconstitution, lyophilized MK-677 powder should be stored away from light between 2°C and 8°C for short-term access, or -20°C for long-term preservation. Once reconstituted with Bacteriostatic Water (0.9% benzyl alcohol preservative), maintain strict refrigeration between 2°C and 8°C. Do not freeze liquid solution.

Cited Scientific References

  1. MK-677 Pharmacological Review & Research Data. National Library of Medicine.

Calculate MK-677 Syringe Units

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Frequently Asked Questions

MK-677 (Ibutamoren) is an orally active, non-peptide selective agonist of the ghrelin receptor. It continuously stimulates profound, long-lasting increases in endogenous GH and IGF-1 levels.

Store lyophilized powder at 2°C to 8°C (refrigerated) or -20°C (frozen for long-term storage). Keep protected from light.